1. O’Connor AM, Bennett CL, Stacey D, Barry M, Col NF, Eden KB et al. Decision aids for people facing health treatment or screening decisions. Cochrane Database Syst Rev 2009:CD001431.
  2. Ottowa Decision Aid Website:
  3. Jeruss JS, Woodruff TK. Preservation of fertility in patients with cancer. N Engl J Med 2009;360:902-11.
  4. Fertility preservation and reproduction in cancer patients. Fertil Steril 2005;83:1622-8.
  5. Lee SJ, Schover LR, Partridge AH, Patrizio P, Wallace WH, Hagerty K et al. American Society of Clinical Oncology recommendations on fertility preservation in cancer patients. J Clin Oncol 2006;24:2917-31.
  6. Petrek JA, Naughton MJ, Case LD, Paskett ED, Naftalis EZ, Singletary SE et al. Incidence, time course, and determinants of menstrual bleeding after breast cancer treatment: a prospective study. J Clin Oncol 2006;24:1045-51.
  7. Green DM, Sklar CA, Boice JD, Jr., Mulvihill JJ, Whitton JA, Stovall M et al. Ovarian failure and reproductive outcomes after childhood cancer treatment: results from the Childhood Cancer Survivor Study. J Clin Oncol 2009;27:2374-81.
  8. Larsen EC, Muller J, Schmiegelow K, Rechnitzer C, Andersen AN. Reduced ovarian function in long-term survivors of radiation- and chemotherapy-treated childhood cancer. J Clin Endocrinol Metab 2003;88:5307-14.
  9. Gelber S, Coates AS, Goldhirsch A, Castiglione-Gertsch M, Marini G, Lindtner J et al. Effect of pregnancy on overall survival after the diagnosis of early-stage breast cancer. J Clin Oncol 2001;19:1671-5.
  10. Ives A, Saunders C, Bulsara M, Semmens J. Pregnancy after breast cancer: population based study. BMJ 2007;334:194.
  11. Infertility (IVF) national success rates:
  12. Azim AA, Costantini-Ferrando M, Oktay K. Safety of fertility preservation by ovarian stimulation with letrozole and gonadotropins in patients with breast cancer: a prospective controlled study. J Clin Oncol 2008;26:2630-5.


Principal Investigators:
Jennifer E. Mersereau, MD, MSCI
Assistant Professor
Reproductive Endocrinology and Infertility
Department of Obstetrics and Gynecology
University of North Carolina at Chapel Hill

Anna R. Brandon, PhD, ABPP
Clinical Psychologist
Clinical Assistant Professor
Women’s Mood Disorders Center
Department of Psychiatry
University of North Carolina at Chapel Hill

Thanks to:
Mrs. Regina Jones, for sharing her story with us.
Robb T. Kehoe, Instructional Media Producer,
UNC School of Medicine

Intervention Development:
Nightlight Productions

Funding support:
Lineberger Comprehensive Cancer Center


If you have any questions, you may contact Dr. Mersereau at
UNC Fertility Preservation
Clinic ph: 919-966-1150
Academic: 919-966-5283
Fax: 919-966-5214